How do microtubule asters grow to fill huge frog eggs?

Updated: Jan 16

by Keisuke Ishihara

Microtubule asters, which are built every time the cell prepares to divide, help the cell find its center. In this video abstract, Keisuke Ishihara tells you what he has learned about how these structures grow. Hint: it's like a relay race! You can read the full paper in the journal eLife.

Keisuke carried out this work as a graduate student in the lab of Tim Mitchison at Harvard, collaborating with Kirill Korolev at Boston University.

Keisuke is now a postdoc at the Max Planck Institute of Molecular Cell Biology and Genetics in Dresden, Germany.

Related resources

You can watch 3 related lectures from Prof. Tim Mitchison! On iBiology.org, watch him discuss Self-Organization in Biology in the following two videos:

Self-organization of microtubule assemblies

Self-organization of meiotic spindles

And watch Tim deliver a lecture on "Spatial organization of a very large cell by microtubules" at the King's International Lecture Series.

#microtubules #celldivision #frogs #biophysics #mathematicalmodel #cell