Substrate’s stiffness drives cell polarization
- May 26
- 1 min read
In this video, we investigate the comportment of cells facing environment of diverse stiffnesses. We show that they can polarize or not, and that this polarization is linked to polarizations of both the substrate and the cell.
This is a perfect example of mechanotransduction: a process through which cells analyze the mechanical properties of their environment and adopt a new conformation depending on their initial state. Understanding those behaviors is helpful in the medical field to better manipulate and heal the cells in our body such as cancer cells.
This video was created by Nathael Deville, a student in the Cell Physics Master at the University of Strasbourg, France.
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