Morphogen gradient scaling during tissue growth


Morphogens are important molecules that give information to cells so that they know their fate. They are particularly important during development when cells should differentiate and divide to form a complex organism. Therefore, understanding morphogen gradient organization during tissue growth and making a link between their dynamic and tissue dynamic could give us more details about how tissue form. Decapentaplegic (or Dpp) is a morphogen that is important during fruit fly wing development. In this video, Samuel Stephan, based on the work of O. Wartlick et al, talks about decapentaplegic gradient dynamic during wing growth and how this gradient scales with tissue size.


Samuel Stephan is a student in the Cell Physics Master at the University of Strasbourg, France.


Related resources: Dynamics of Dpp signaling and proliferation control https://pubmed.ncbi.nlm.nih.gov/21385708/

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